Apr302018 by DocNo Comments

Metformin Treats Type 2 Diabetes

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[caption id="attachment_254" align="alignleft" width="150"] logo created by RKL[/caption] Metformin or Glucophage ranks as the first choice in treating Type 2 Diabetes when diet and exercise fail.  This drug remains one of the true bargains in American medicine – especially in diabetes care - typically costing less than $30 a month. Of course the main issue in Type 2 Diabetes remains excess body fat.  Cure by weight loss would be preferable to treatment by pill or injection.  Metformin offers the opportunity to decrease blood sugar without the risk of hypoglycemia when prescribed as the sole agent. Unfortunately as time progresses, most overweight individuals continue to add extra pounds which requires supplemental therapy.  Metformin may be combined with most other classes of anti-diabetic therapy. Metformin functions by altering a number of metabolic…
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Apr292018 by Doc1 Comment

Wellbutrin | Bupropion | Antidepressant

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[caption id="attachment_254" align="alignleft" width="150"] logo created by RKL[/caption] Originally marketed by its brand name Wellbutrin, most people receive the far less expensive generic bupropion.  The drug remains one of the most frequently prescribed anti-depressants capitalizing on the widespread perception it causes fewer side effects.  Arguably less weight gain and fatigue occur with bupropion than with other anti-depressants.  Additionally it may alleviate some of the sexual dysfunction associated with members of the SSRI family such as Prozac, Zoloft and Celexa. While physicians tend to champion one anti-depressant over another, statistics fail to reveal substantial difference between drugs commonly utilized to combat the disorder.  Due to individual sensitivity, some people may respond more favorably to one drug or experience fewer side effects compared to other options.  Interestingly for the majority of people,…
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Apr282018 by DocNo Comments

Nuplazid Adverse Reactions

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Potentially severe adverse reactions including death warrant reconsideration of Nuplazid.  The drug continues to be heavily promoted to the public on television commercials and to the profession in journal advertisements.  Unfortunately Nuplazid offers few benefits compared to the major risk of complications.  Marketed as a breakthrough therapy to combat the hallucinations and delusions associated with Parkinson’s Disease, it barely surpassed the merits of an inactive placebo.  Except the placebo was neither associated with death nor did it cost anywhere near the staggering $30,000 a year commanded by Nuplazid.   During Nuplazid’s short time on the market, the Food and Drug Association Adverse Events Reporting System or FARES received more than 5700 reports of problems associated with the drug.  This included more than 1800 serious reactions and 712 deaths.  Although FARES…
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