Erectile Dysfunction or simply ED at least temporarily affects more than 40% of men beyond age 40. The popular family of inhibitors of an enzyme known as PDE5 include Cialis, Viagra and Levitra.  All of these drugs work basically in a similar manner.  Selection of which to choose relate more to personal preference and cost than other factors.  These drugs require sexual stimulation and release of nitric oxide from the tissues in order to function.  Cialis neither functions as an aphrodisiac nor as a treatment for premature ejaculation..

The typical dose of Cialis is 10 mg no more frequently than daily.   Results appear within 30-45 minutes when combined with sexual stimulation.  Due to its slow metabolism, a considerable amount remains in the tissues for more than 17 hours.  Lasting longer than other members of the class earned it the nickname of “The Weekend Pill”.   Instead of taking the pill prior to planned sexual activity, a smaller daily dose of 2.5 or 5.0 mg offers advantages for unplanned activities.  The drug also may offer minor and temporary assistance to men with difficulty urinating due to an enlarged prostate.

Side effects tend to relate to dilation of blood vessels and may include a variety of muscle aches and stuffy nose or indigestion.  More serious are a precipitous fall in blood pressure if combined with certain medicines especially nitroglycerin prescribed for relief of chest pain.  Hearing problems and in rare circumstances loss of vision may result.

When it became available in 2009 the price for one pill ranged between $13-$16 and the drug company reaped considerable profit.  Unfortunately greed and relative lack of choice supervened and now the cash price for just one tablet has soared by as much as 500% to as much as $80.  But there is light at the end of the tunnel, in 2017 a generic alternative was allowed in the United Kingdom and in several years will be available in the United States.  A generic sildenafil is currently marketed in the United States for a drastically reduced price.

 

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